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Before Willem Dafoe received the role of the Green Goblin, both Nicolas Cage and John Malkovich were offered the role. Malkovich and Dafoe starred together in Shadow of the Vampire (2000), which was produced by Nicolas Cage.

David Fincher was offered the chance to direct, but turned it down.

James Franco auditioned to play Peter Parker, but was cast as Harry Osborn instead.

Sam Raimi was not Sony's first choice as director. Others considered were Jan Debont, James Cameron, and Ang Lee.

James Cameron was originally lined up to direct, and even wrote a detailed treatment that was well received by the people at Marvel Comics. Cameron moved on when the film rights were caught between studios and the only things to remain of his treatment are the biological web shooters.

A welder building sets for the movie was killed 6 March 2001, when a crane toppled onto a construction basket in which he was riding and struck him in the head.

Zach Hudson, the stunt double for Tobey Maguire, fractured his leg after a stunt went wrong and he slammed into a brick wall.

The original trailer for the movie depicted a theft of a bank, with the robbers making a getaway in a helicopter. A close-up of the helicopter was shown, until the helicopter stopped, apparently caught in mid-air. As the camera zoomed out, it was shown that the helicopter was caught in a spider web, suspended between the two towers of the World Trade Center. After the attacks on the towers 11 September 2001, however, the trailer was changed.

In the comics, Peter Parker designed and made Spider-Man's synthetic spider web and the mechanical wrist guns that fire it. In the movie he shoots the web from his own body. Director Sam Raimi answered the protests of comic book fans saying that it was more credible to have Peter shoot web this way than for a high school boy to be able to produce a wonder adhesive in his spare time that 3M could not make.

artist_tobey_maguire_(ec) said he had never read a Spider-Man comic book, but that he took the role because he liked the script.

Director Sam Raimi owns a yellow 1973 Oldsmobile Delta 88 which he tries to place in any of his films when appropriate.

Freddie Prinze Jr and Leonardo Dicaprio were both considered for the role as Peter Parker/Spider-Man.

The writers Alvin Sargent and Scott Rosenberg contribute to the last un-credited re-write on the shooting script.

The owners of the billboards on Times Square are suing Sony and those involved with the production of Spider-Man 'for digitally superimposing advertisements for other companies over their billboard space in the film'.

Facts courtesy of Internet Movie Database and Columbia Pictures.

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